nRichDX Revolution System
Unprecedented sample prep volumes, unparalleled simplicity
The nRichDX Revolution System is a semi-automated liquid biopsy sample prep platform that is designed to purify cfDNA, exosomes, microvesicles, CTCs, and other cancer biomarkers from 3 – 50 mL of blood, plasma, urine and other biological fluids. The patented technology is centered on the single-use Revolution nRicher Cartridge that combines extraction, enrichment, and concentration of CTCs, exosomes, or cfDNA without the need for transfer steps.
The nRichDX Revolution System represents an unprecedented, innovative solution: combining an industry-leading target recovery rate up to 80% with the ability to process clinical sample volumes up to 50 mL. The combination of larger samples and higher recovery rates translates to significantly more analytes to deliver accurate molecular diagnostic results at low allele frequencies.
The Revolution System Includes:
- Revolution Processor - PN 10081
- Revolution Cartridge Rack - PN 100305
- Drip Tray - PN 100140
- Revolution Mag Capsules (Box of 8) - PN 10080
- Revolution Mag Rack - PN 10082
Revolution Mag Capsule
Each Revolution Mag Capsule is designed to work exclusively with the nRichDX Revolution nRicher Cartridge for the isolation and purification of liquid specimens.
Revolution Mag Rack
An essential part of the elution process, the Revolution Mag Rack holds 1-8 of the 2 mL Revolution microvial tubes that are an integrated component of the Revolution nRicher Cartridge.
Revolution nRicher Cartridge
The Revolution nRicher Cartridge embodies a patented sample processing method that combines extraction, enrichment, and concentration of liquid biopsy samples without the need for transfer steps. The elimination of transfer steps facilitates a simple workflow and enables an industry-leading target recovery rate up to 80%.
The Revolution nRicher Cartridge may not be purchased separately but is a component of the Revolution cfDNA Max 10 Kit and Revolution cfDNA Max 20 Kit.
Revolution nRicher Cartridge pictured inside Revolution Cartridge Rack.
Revolution Cartridge Rack
The Revolution Cartridge Rack holds 1 – 8, Revolution nRicher Cartridges and is an essential part of the nRichDX isolation and purification process.
Revolution cfDNA Isolation Kits
Revolution cfDNA Max 10 Kit
The Revolution cfDNA Max 10 Kit includes (24) Revolution nRicher Cartridges and sufficient reagents to perform the following cfDNA extractions from plasma or urine:
- 24 - 5 mL preps or
- 12 - 10 mL preps
Revolution cfDNA Max 20 Kit
The Revolution cfDNA Max 20 Kit includes (8) Revolution nRicher Cartridges and sufficient reagents to perform the following cfDNA extractions from plasma or urine:
- 8 - 15 mL preps or
- 6 - 20 mL preps
Revolution cfDNA Reagent Kit 0.5
The Revolution cfDNA Reagent Kit provides “reagents only” to enable the use of any excess Revolution nRicher Cartridges. No Revolution nRicher Cartridges are included. This kit has sufficient reagents to perform the following cfDNA extractions from plasma or urine:
- 12 - 5 mL preps or
- 6 - 10 mL preps or
- 4 - 15 mL preps or
- 3 - 20 mL preps