Products

Summary Product Benefits:

• Convenient - 5 individual thaw-and-use tubes
  
• Control -  determine the efficiency of your extraction method
  
• Standard - acknowledged standard for spike-and-recovery cfDNA extraction experiments

The nRichDX cfDNA Reference Standard contains 5 single-use tubes containing 1 mL at a 1 ng/µl concentration in TE Buffer. Comparing the spike-in amount to the recovery amount, the percent recovery is determined.

The cfDNA Reference Standard contains mononuclear DNA (mnDNA) containing the KRAS G12V and TP53 Arg158Leu variants, which are established standards for spike-and-recovery extraction analysis for cfDNA*.

The expected mnDNA size is 150 bp. mnDNA is obtained from the NCI-H441 lung cancer cell line. Dinucleosomes and trinucleosomes may also be observed at the given multiples of 340 bp and 560 bp.