Revolution Plus System
PN 2000-PLUS
The nRichDX Revolution Plus Sample Prep System is designed to purify cfDNA, cfRNA from 1 mL up to 50 mL of blood, plasma, urine, and other biological fluids and up to 100 mL for CTCs.
The patented technology is centered on the single-use Revolution nRicher Cartridges that combine extraction, enrichment, and concentration without the need for yield-lowering sample transfer steps, re-elutions, or pooling multiple extractions from the same sample. Revolution Sample Prep handles small and large volume extractions with ease.
Revolution Plus is able to operate in two different modes using separate USB Keys. "Kit Mode" for extraction according to the latest approved Revolution Protocol and a user-programmable "Research Mode" (available separately).
The IVD-labeled* nRichDX Revolution Plus Sample Prep System delivers better performance, workflow, and flexibility with solutions engineered to easily deliver the highest yields of rare analytes from an unequaled range of liquid biopsy sample types and sample volumes.
*IMPORTANT NOTE: The Revolution cfDNA and cfTNA Kits when used in "Kit Mode" on the Revolution Plus Instrument are IVD-labeled. The Revolution CTC Enrichment Kit is labeled, "For Research Use Only. Not for use in diagnostic applications." even when the IVD-labeled Revolution Plus Instrument is used in Kit Mode
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Revolution cfDNA Max 20 Kit
PN 100131
Summary Product Benefits:
- Better Performance - higher yields of cfDNA means greater assay sensitivity and fewer 'QNS' assay failures
- Greater Flexibility - widest range of input sample volume (1 mL - 20 mL) of any automated extraction kit with the unique nRicher Cartridge
- Easier Workflow - as compared to other methods which require tedious vacuum manifolds, tube extenders, manual pre-concentration steps, re-elutions, and extraction sample pooling for larger per-sample volumes
The IVD-labeled Revolution cfDNA Max 20 Kit includes (24) Revolution nRicher Cartridges and sufficient reagents to perform the following cfDNA extractions from plasma or urine:
- (24) 1-5 mL preps or
- (12) 6-10 mL preps or
- (8) 11-15 mL preps or
- (6) 16-20 mL preps
Eluted nucleic acid suitable for NGS, PCR, and other downstream molecular biology assays.
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Revolution cfDNA Max 20XL Kit
PN 100155
Summary Product Benefits:
- All the benefits and features of the Revolution cfDNA Max 20 Kit shown above - optimized for samples of >10 mL
The IVD-labeled Revolution cfDNA Max 20XL Kit includes (8) Revolution nRicher Cartridges and sufficient reagents to perform the following cfDNA extractions from plasma or urine:
- (8) 11-15 mL preps or
- (6) 16-20 mL preps
Eluted nucleic acid suitable for NGS, PCR, and other downstream molecular biology assays.
Resources
Revolution cfDNA Reagent Kit
PN 100119
Summary Product Benefits:
- Flexibility - The same cfDNA Max 20 Revolution reagents without the nRicher Cartridges
- Efficiency - Get full utilization of all your kit's nRicher Cartridges
The IVD-labeled Revolution cfDNA Reagent Kit provides reagents only to enable the use of any excess Revolution nRicher Cartridges. No Revolution nRicher Cartridges are included. This kit has sufficient reagents to perform the following cfDNA extractions from plasma or urine:
- (24) 1-5 mL preps or
- (12) 6-10 mL preps or
- (8) 11-15 mL preps or
- (6) 16-20 mL preps
Resources
Revolution cfTNA Max 20 Kit
PN 100499
Summary Product Benefits:
- Better Performance - higher yields of cfDNA means greater assay sensitivity and fewer 'QNS' assay failures
- Greater Flexibility - widest range of input sample volume (1 mL - 20 mL) of any automated extraction kit with the unique nRicher Cartridge
- Easier Workflow - as compared to other methods which require tedious vacuum manifolds, tube extenders, manual pre-concentration steps, re-elutions, and extraction sample pooling for larger per-sample volumes
The IVD-labeled Revolution cfTNA Max 20 Kit may be used to isolate circulating cell-free Total Nucleic Acid (cfTNA) or cfRNA, using an optional DNAse digestion step. The kit includes (24) Revolution nRicher Cartridges and sufficient reagents to perform the following cfTNA extractions from plasma or urine:
- (24) 1-5 mL preps or
- (12) 6-10 mL preps or
- (8) 11-15 mL preps or
- (6) 16-20 mL preps
Eluted nucleic acid suitable for NGS, PCR, and other downstream molecular biology assays.
Resources
Revolution cfTNA Max 20XL Kit
PN 100500
Summary Product Benefits:
- All the benefits and features of the Revolution cfTNA Max 20 Kit shown above - optimized for samples of >10 mL
The IVD-labeled Revolution cfTNA Max 20XL Kit may used to isolate circulating cell-free Total Nucleic Acid (cfTNA) or cfRNA, using an optional DNAse digestion step. The kit includes (8) Revolution nRicher Cartridges and sufficient reagents to perform the following cfDNA extractions from plasma or urine:
- (8) 11-15 mL preps or
- (6) 16-20 mL preps
Eluted nucleic acid suitable for NGS, PCR, and other downstream molecular biology assays.
Resources
Revolution cfTNA Reagent Kit
PN 100487
Summary Product Benefits:
- Flexibility - The same cfTNA Max 20 Revolution reagents without the nRicher Cartridges
- Efficiency - Get full utilization of all your kit's nRicher Cartridges
The IVD-labeled Revolution cfTNA Reagent Kit provides reagents only to enable the use of any excess Revolution nRicher Cartridges. No Revolution nRicher Cartridges are included. This kit has sufficient reagents to perform the following cfTNA extractions from plasma or urine:
- (24) 1-5 mL preps or
- (12) 6-10 mL preps or
- (8) 11-15 mL preps or
- (6) 16-20 mL preps
Resources