Careers at nRichDX

Key Responsibilities

Kit QC & Functional Testing (Primary)

• Own and execute functional testing plans for commercial kit lots including incoming components, in-process materials, and final kit performance testing.
• Run routine QC assays, including as applicable:
• qPCR/RT-qPCR for recovery, inhibition checks, and linearity.
• TapeStation/Bioanalyzer for size profiles, integrity, and yield QC.
• Fluorometric quantification including Qubit, PicoGreen, and RiboGreen.
• Extraction performance checks including yield, reproducibility, carryover, and contamination controls.
• Prepare and process biological samples including plasma, urine, whole blood, and contrived controls according to SOPs.
• Track lot performance, generate QC summaries and CoA-support data, and flag out-of-specification trends.
• Investigate deviations and failures, perform root-cause analysis, and recommend corrective actions with R&D, Manufacturing, and Quality.

Cross-Functional Support

• Partner with Manufacturing to ensure smooth tech transfer and readiness for scale, including materials, build records, and test readiness.
• Coordinate with Quality on documentation, change-control support, and release criteria.
• Support troubleshooting of customer-reported issues by recreating conditions and documenting findings.

Routine R&D Work (Secondary)

• Assist with protocol optimization, method verification, and robustness studies.
• Support automation workflows as needed including Hamilton or internal platforms, with run setup, execution, and data review.
• Maintain lab organization, instrument upkeep, reagent preparation, and inventory management.
• Maintain high-quality documentation including lab notebooks, raw data files, SOP updates, and summary reports.

Qualifications

Required

• B.S. in Molecular Biology, Biochemistry, Chemistry, Biomedical Engineering, or a related field. M.S. preferred.
• 2+ years of hands-on experience in a molecular biology lab. Industry experience preferred.
• Demonstrated experience with DNA/RNA extraction and qPCR/RT-qPCR.
• Strong attention to detail and comfort working in a structured, repeatable testing environment.
• Ability to produce clear documentation and communicate results to cross-functional teams.

Preferred

• Experience with cfDNA/cfRNA/cfTNA workflows, low-input samples, or liquid biopsy.
• Experience with TapeStation/Bioanalyzer, NGS library QC, or inhibition and contamination-control strategies.
• Familiarity with GxP/ISO concepts, change control, deviations, and data-integrity principles.
• Experience supporting automation platforms including Hamilton.
• Comfortable analyzing data in Excel. Basic statistics, graphing, or scripting experience is a plus.

Skills & Attributes

• Highly organized, reliable, and execution-focused.
• Strong troubleshooting mindset and ability to identify patterns and trends across lots.
• Collaborative and comfortable working with R&D, Manufacturing, and Quality.
• Able to manage multiple tests and priorities while maintaining accuracy.

Working Conditions

• Lab-based role handling human-derived specimens with appropriate training and PPE.
• May require occasional schedule flexibility to support builds, releases, or time-sensitive studies.

Success Metrics First 3–6 Months

• Independently executes the functional testing plan for kit lots with minimal supervision.
• Produces consistent, audit-ready QC documentation and summaries.
• Helps reduce retests and failures through early detection of issues and clear root-cause investigations.
• Contributes meaningfully to routine R&D studies and continuous-improvement efforts.